Clinical Simulation Practice Test 2026 – Your All-in-One Guide to Exam Success!

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What does the Hering-Breuer inflation reflex do?

Increases inspiration

Stops inspiration and stimulates expiration

The reflex is a protective mechanism that prevents over-expansion of the lungs during deep breaths. When the lungs inflation stretches receptors in the airway walls, these sensors send signals via the vagus nerve to the brainstem. The respiratory centers then dampen the inspiratory drive and shift toward expiration, effectively stopping further inhalation and initiating exhalation. This helps keep the alveoli from being overdistended and is especially noticeable in newborns or during forceful or rapid breathing.

Coughing is triggered by irritants in the airways, not by pulmonary stretch. Producing sleep is governed by broader sleep-wake regulation, not this reflex.

Causes coughing

Produces sleep

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